WebApr 1, 2024 · Intranasal drug delivery is convenient and provides a high bioavailability but requires the use of mucoadhesive nanocarriers. Chitosan is a well-established polymer for mucoadhesive applications but can suffer from poor cytocompatibility and stability upon administration. In this work, we present a method to obtain stable and cytocompatible … WebNov 20, 2024 · 1. Introduction. The mucosal route is gaining attention for noninvasive drug delivery via the oral, nasal, pulmonary or vaginal routes [].At the same time, nanoparticle technology has also come to the forefront as a viable drug delivery strategy, presenting opportunities for controlled release, protection of active components from enzymatic or …
Advances in Chitosan-Based Nanoparticles for Drug Delivery
WebOct 6, 2024 · The Feasibility of the Use of Chitosan-Based Nanoparticles as Drug Delivery Systems in the Philippines Nanotechnology and its applications have been some of the most promising research and development (R and D) areas of the decade ( Wong et al., 2013 ; Conde, 2015 ; Zakeri and Lu, 2015 ). WebNov 14, 2024 · Chitosan-based nanoparticles (CSNPs) for pH-sensitive drug delivery systems • Cationic property causes it to approach cell membranes more easily and allows ionic cross-linkage with multivalent anions. • Presence of amino groups in large quantities on chains of CS, its ionization makes CS molecules pH-sensitive. optic gallery ann and 95
Potential of different salt forming agents on the formation of chitosan …
WebFe 3 O 4 NP have been reported to up-regulate ROS including H 2 O 2 which potentially play a key role in biomedical applications especially for targeted drug delivery. 25 The assessment of anticancer drug-loaded nanoparticles and their effect on the induction of cell apoptosis, and the extent of the Fe 3 O 4 NP activated ROS-mediated ... WebJun 15, 2024 · Chitosan, as the unique positively charged natural polysaccharide, has been widely used for drug delivery. It is a linear polysaccharide composed of randomly distributed β-(1-4)-linked D-glucosamine residues and N-acetyl-D-glucosamine units (Fig. 1).Besides possessing the merits of most natural polysaccharides, such as high … WebFeb 28, 2024 · Chitosan nanoparticles as a drug delivery system is a hot topic in chitosan research. There have been reports of the use of chitosan nanoparticles as vaccine adjuvants, encapsulation of insulin into chitosan nanoparticles, chitosan nanoparticles in targeted drug delivery, and various other applications of drug … porthminster cafe webcam