Phorbol 12-myristate 13-acetate storage
WebDescription. Activates protein kinase C and promotes skin tumors in mice. PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to … WebPhorbol 12-myristate 13-acetate PKC activator Replaces Prod. #: ALX-445-004 PKC activator (10-100 ng/ml). Most commonly used phorbol ester. Causes an extremely wide range of effects in cells and tissues. Very potent mouse skin tumor promoter. Inhibits apoptosis induced by Fas, but induces apoptosis in HL-60 promyelocytic leukemia cells.
Phorbol 12-myristate 13-acetate storage
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Web12-O-Tetradecanoylphorbol-13-acetate ( TPA ), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate ( PMA) is a diester of phorbol. It is a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC). WebThere were no significant differences in the proportions with residual plasma viremia ≥1 copies/mL or in phorbol 12-myristate 13-acetate/ionomycin-induced virus production …
WebStorage. Store lyophilized or in solution at -20ºC, desiccated. Protect from light. In lyophilized form, the chemical is stable for 24 months. ... / PMA (phorbol-12-myristate-13-acetate) is the most commonly used phorbol ester. It binds and activates protein kinase C, causing a wide range of effects in cells and tissues (1,2). TPA has been ... WebPhorbol 12-myristate 13-acetate PMA 16561-29-8 A PKC activator, including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. supplier price ...
WebPhorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References Brochures Data Sheet Citations WebView All Cold Storage Products; Influenza, Virus, and COVID-19 Testing. Flu and Virus Testing. COVID Testing Kits; Multiplex COVID Testing Kits ... PMA, TPA; Phorbol 12-myristate 13-acetate is a phorbol ester. It works as a tumor promoter and is involved in gene transcription, cell growth, differentiation, programmed cell death, immune pathway ...
WebMar 14, 2024 · THP-1 cells differentiated with phorbol 12-myristate 13-acetate (PMA) are widely used as a model for function and biology of human macrophages. However, the conditions used for differentiation, particularly the concentration of PMA and the duration of treatment, vary widely.
howards grove high school girls basketballWeb500582 Sigma-Aldrich InSolution™ Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Download Zoom MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS References Data Sheet Synonyms: 12-O-Tetradecanoyl-phorbol-13-acetate, PMA, TPA Primary Target: PKC 500582 howards grove high school calendarWebSep 16, 2011 · The second set of experiments was a model of ROS production based on the oxidant activities of human monocytes activated with phorbol-12-myristate-13-acetate (PMA), that we designed to study the effect of the plant extracts on the cellular ROS production in inflammation-like conditions, using a fluorescence technique with 2′,7 ... how many kids struggle in schoolWebPhorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a reversible, highly potent activator of protein kinase C (PKC), including Group A and Group B isoforms (Blumberg). PMA activates PKC isoforms through the binding of the C1 domain (Hurley et al.). howards grove high school facebookWebexpression in anti-CD28/phorbol 12-myristate 13-acetate-stimulated T cells. Expression of MICA on activated T cells involved interleukin-2-dependent signaling routes triggered by … how many kids steve harvey have with marjorieWebM4647-Phorbol-12-myristate-13-acetate-COA.pdf. ... 检测报告检测报告 目录号：M4647产品名：Phorbol 12-myristate 13-acetateCAS号：16561-29-8物理和化学性质物理和化学性质分子式：C H O分子量：616.83溶解性：DMSO 20 mg/mL长期储存：-20C 冷藏结构式：分析数据分析数据HPLC：纯度 98%H-NMR ... howards grove high school volleyballWebJun 5, 2015 · For this, the extensively investigated in vitro latency model of THP-1 monocytes was used: While HCMV infection of non-differentiated THP-1 cells results in latent carriage of the viral genome, the cells become permissive for HCMV lytic infection after induction of cellular differentiation by treatment with phorbol 12-myristate 13 … howards grove high school boys basketball